{"id":22589,"date":"2023-03-06T17:15:36","date_gmt":"2023-03-06T16:15:36","guid":{"rendered":"https:\/\/www.hmg-systems-engineering.com\/prepare-study-personalized-medication-reduces-side-effects-by-30\/"},"modified":"2023-07-19T10:03:48","modified_gmt":"2023-07-19T08:03:48","slug":"prepare-study-personalized-medication-reduces-side-effects-by-30","status":"publish","type":"post","link":"https:\/\/www.hmg-systems-engineering.com\/en\/prepare-study-personalized-medication-reduces-side-effects-by-30\/","title":{"rendered":"PREPARE study: Personalised medication reduces side effects by 30%"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"22589\" class=\"elementor elementor-22589 elementor-21307\" data-elementor-settings=\"{&quot;ha_cmc_init_switcher&quot;:&quot;no&quot;}\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"has_eae_slider elementor-section elementor-top-section elementor-element elementor-element-50de70f elementor-section-height-min-height elementor-section-boxed elementor-section-height-default elementor-section-items-middle\" data-eae-slider=\"22106\" data-id=\"50de70f\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;,&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-976d5b3\" data-eae-slider=\"43705\" data-id=\"976d5b3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f6c12c6 elementor-widget elementor-widget-spacer\" data-id=\"f6c12c6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c992235 elementor-widget elementor-widget-spacer\" data-id=\"c992235\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2a643e2 elementor-widget elementor-widget-heading\" data-id=\"2a643e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">PREPARE study<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-05f943c elementor-widget elementor-widget-heading\" data-id=\"05f943c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Personalised Medication<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_eae_slider elementor-section elementor-top-section elementor-element elementor-element-ab4b5a6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-eae-slider=\"43063\" data-id=\"ab4b5a6\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a923385\" data-eae-slider=\"7347\" data-id=\"a923385\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-32f8706 elementor-widget elementor-widget-heading\" data-id=\"32f8706\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">PREPARE study: Personalised medication reduces side effects by 30%<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_eae_slider elementor-section elementor-top-section elementor-element elementor-element-0e7597f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-eae-slider=\"22099\" data-id=\"0e7597f\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-78c9e16\" data-eae-slider=\"86434\" data-id=\"78c9e16\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1053de1 elementor-widget elementor-widget-text-editor\" data-id=\"1053de1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>As an innovative company in the field of personalised medication, we are pleased to share the promising results of the PREPARE study, which was conducted by the international UPGx consortium.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_eae_slider elementor-section elementor-top-section elementor-element elementor-element-b474efe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-eae-slider=\"70343\" data-id=\"b474efe\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-49d100d\" data-eae-slider=\"5838\" data-id=\"49d100d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2445f73 elementor-widget elementor-widget-text-editor\" data-id=\"2445f73\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The PREPARE study (PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions), investigated the use of a drug passport that includes genotyping of 12 genes and 50 genetic variants that affect how drugs are broken down in the body.<\/p>\n<p><span style=\"letter-spacing: 0px;\">The study, which involved 6,944 patients from seven European countries, suggests that the use of a personalised drug passport can reduce the number of adverse drug reactions in the treatment of depression by 30%.<\/span><\/p>\n<p>Funding took place under the European Horizon 2020 research and innovation program. The UPGx consortium received a grant of 14.5 million euros for the project. &#8220;Horizon 2020&#8221; is the largest research and innovation program of the European Union and aims to promote innovation and scientific excellence in Europe.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-d2084e6\" data-eae-slider=\"79220\" data-id=\"d2084e6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-89b4643 elementor-widget elementor-widget-image\" data-id=\"89b4643\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/www.hmg-systems-engineering.com\/wp-content\/uploads\/2023\/03\/ENG-Infographic-PREPARE-studie-1.png\" class=\"attachment-large size-large wp-image-22322\" alt=\"\" srcset=\"https:\/\/www.hmg-systems-engineering.com\/wp-content\/uploads\/2023\/03\/ENG-Infographic-PREPARE-studie-1.png 1024w, https:\/\/www.hmg-systems-engineering.com\/wp-content\/uploads\/2023\/03\/ENG-Infographic-PREPARE-studie-1-300x225.png 300w, https:\/\/www.hmg-systems-engineering.com\/wp-content\/uploads\/2023\/03\/ENG-Infographic-PREPARE-studie-1-768x576.png 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"has_eae_slider elementor-section elementor-top-section elementor-element elementor-element-7cf7402 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-eae-slider=\"53090\" data-id=\"7cf7402\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;_ha_eqh_enable&quot;:false}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"has_eae_slider elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3121296\" data-eae-slider=\"16272\" data-id=\"3121296\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-04ba3a9 elementor-widget elementor-widget-text-editor\" data-id=\"04ba3a9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The results of the study underline the importance of pharmacogenetic analysis for the prevention of adverse drug reactions and show that individualised medication based on the patient&#8217;s genetic predisposition leads to better treatment outcomes. <\/p>\n<p>For PGXperts, this confirms the importance of our work and encourages us to continue our development efforts.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bcb01d1 elementor-widget elementor-widget-heading\" data-id=\"bcb01d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">PGXperts InteractionCheck - individualised medication with pharmacogenetic<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96fcfb4 elementor-widget elementor-widget-text-editor\" data-id=\"96fcfb4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>With PGXperts InteractionCheck, interaction risks between drugs, active ingredients, foods and lifestyle habits as well as genetic variations can be identified in less than 1 minute. Interactions are clearly classified according to their severity and described in detail. The clear presentation of genetic interaction risks allows rapid identification of patients who could benefit from pharmacogenetic analysis. <span style=\"letter-spacing: 0px;\">The InteractionCheck is available as a web application and for Android and iOS devices. It can thus be used both as an inpatient tool and on the road, for example, during home visits or emergency interventions.<\/span><\/p>\n<p>For more information about the PGXperts InteractionCheck, please visit: <a style=\"background-color: #ffffff;\" href=\"http:\/\/www.pgxperts.com\" target=\"_blank\" rel=\"noopener\">www.pgxperts.com<\/a><\/p>\n<p>More information about U-PGx and the results of the PREPARE study can be found at: <a href=\"https:\/\/upgx.eu\/results\/\">https:\/\/upgx.eu\/results\/<\/a><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>As an innovative company in the field of personalised medication, we are pleased to share the promising results of the PREPARE study, which was conducted by the international UPGx consortium.<br \/>\nIn the PREPARE-Studiy (\u201ePREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions\u201c), the use of a drug passport containing genotyping of 12 genes and 50 genetic variants that affect drug degradation in the body was investigated. <\/p>\n","protected":false},"author":3,"featured_media":22324,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[56],"tags":[],"class_list":["post-22589","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blogpost-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>PREPARE study: Personalised medication reduces side effects by 30% - HMG Systems Engineering GmbH<\/title>\n<meta name=\"description\" content=\"As an innovative company in the field of personalised medication, we are pleased to share the promising results of the PREPARE study, which was conducted by the international UPGx consortium. 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